Complex diseases can affect major organ systems, including the immune, cardiovascular, musculoskeletal and nervous systems. These diseases can present with varying phenotypes and their underlying mechanisms are poorly understood. Identifying complex disease etiology requires analyses of heritable and nonheritable mutations, transcriptional modifications, and pathway regulation. Illumina offers array and next-generation sequencing (NGS) solutions to empower your research.
Reliably sequence exomes or large numbers of genes (e.g. > 50 genes) using robust and straightforward workflows. Hybridization-based enrichment is a useful strategy for analyzing specific genetic variants in a given sample. Use target enrichment solutions within your complex disease research to deliver dependable results across a wide range of input types and quantities.Learn More
Immune cells work to protect the body from foreign invaders including viruses, bacteria, and parasites. Mutations and environmental factors can cause the immune system to malfunction and attack the body it is meant to protect. Many complex autoimmune disorders exist that are poorly understood. Complete microarray and NGS solutions from Illumina can provide insights to advance research.Learn More
The central and peripheral nervous systems are targets for complex diseases, including neurodegenerative diseases, psychiatric conditions, and others. Recent NGS studies are revealing the full complexity of neurological disorders. Illumina has the array and NGS tools needed to make this research possible.Learn More
Many complex diseases exist that fall under cardiology, metabolism, and other research areas. These include diabetes, heart conditions, osteoporosis, and many more. Customizable microarray and NGS solutions from Illumina can provide detailed insight into the potential genetic causes and functional consequences of variation.Learn More