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Local Run Manager for intuitive onboard data analysis

Local Run Manager Software

Automatic On-Instrument Data Analysis

Local Run Manager is an integrated on-instrument solution for creating a sequencing run, monitoring run status, analyzing sequencing data, and viewing results. It integrates with the instrument control software and is easily accessed through a web browser, with a user-friendly touchscreen interface.

Local Run Manager automatically performs on-instrument data analysis. Various optional software modules are available to perform analysis procedures designed for different library types. Local Run Manager currently works with the analysis software modules listed below.

Find Compatible Library Prep Kits

Most Local Run Manager analysis modules will prompt you to select a library prep kit for a given run. Find out which kits are compatible with each Local Run Manager software analysis module.

View Compatible Kits

Available Analysis Modules

TruSight Tumor 15 Analysis Module

Analyzes and generates a filtered report for samples prepared using the TruSightTumor 15 assay for 15 genes associated with solid tumors.

TruSight Tumor 15 Module
Amplicon Analysis Module

Enables variant detection and streamlined analysis of Illumina TruSeq Amplicon panels.

Amplicon Analysis Module
Amplicon DS Analysis Module

Enables streamlined analysis of the Illumina TruSight Tumor 26 and dual pool (dual strand) TruSeq Custom Amplicon panels.

Amplicon DS Analysis Module
DNA Enrichment Analysis Module

Aligns reads against a whole genome reference and performs variant analysis for specified regions of interest.

DNA Enrichment Analysis Module
Small RNA Analysis Module

Aligns reads and outputs hits. Performs optional novel precursor discovery and pairwise differential expression analysis.

Small RNA Analysis Module
Targeted RNA Analysis Module

Analyzes RNA samples prepared using TruSeq Targeted RNA Expression Kits. Aligns reads, quantifies relative expression.

Targeted RNA Analysis Module
Resequencing Analysis Module

Aligns reads and performs variant analysis for whole-genome sequencing of small genomes.

Resequencing Analysis Module
GenerateFASTQ Analysis Module

Generates demultiplexed FASTQ files for further downstream analysis.

GenerateFASTQ Analysis Module

Technical Support Bulletins

Technical support bulletins contain details about common procedures and answers to frequently asked questions. See the following bulletins for more information about using Local Run Manager.

Download Analysis Modules or Get Support

Download a specific analysis software module of interest, or access Local Run Manager technical support information.

Download Local Run Manager Modules
Access Local Run Manager Support
For Research Use Only

Not for use in diagnostic procedures (except as specifically noted).

Innovative technologies

At Illumina, our goal is to apply innovative technologies to the analysis of genetic variation and function, making studies possible that were not even imaginable just a few years ago. It is mission critical for us to deliver innovative, flexible, and scalable solutions to meet the needs of our customers. As a global company that places high value on collaborative interactions, rapid delivery of solutions, and providing the highest level of quality, we strive to meet this challenge. Illumina innovative sequencing and array technologies are fueling groundbreaking advancements in life science research, translational and consumer genomics, and molecular diagnostics.

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