Francesco Fiorentino, Director of Genoma Molecular Genetics Laboratory, Rome, Italy, discusses the high-throughput, high-resolution advantages of next-generation sequencing http://technology.illumina.com/technology/next-generation-sequencing.html for preimplantation genetic screening http://clinical.illumina.com/clinical/reproductive-genetic-health/clinical-labs/preimplantation-genetic-screening.html. He also touches upon how NGS can aid the detection of segmental imbalances in embryos, for translocation , and single gene disorders http://clinical.illumina.com/clinical/reproductive-genetic-health/clinical-labs/preimplantation-genetic-diagnosis.html. In closing, he highlights the results of a recent study that showed that the VeriSeq PGS Kit delivers http://products.illumina.com/products/veriseq-pgs.html a high degree of concordance with array-CGH, as well as high levels of implantation and pregnancy rates. Clinical Paper Fiorentino F, Bono S, Biricik A, et al. Application of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cycles. Human Reproduction.