The Infinium OncoArray-500K BeadChip content draws on many features of the Collaborative Oncological Gene-environment Study (iCOGS) array. Developed in collaboration with leading experts from the OncoArray consortium, the Infinium OncoArray-500K offers the most comprehensive, highest-density BeadChip available for researching cancer predisposition and risk. The Infinium OncoArray-500K contains ~500K SNPs with a genome-wide backbone of ~275K tag SNPs. Additional SNPs include genetic variants associated with many cancers plus SNPs covering ancestry, quantitative traits, pharmacogenetics, and fine-mapping of common cancer susceptibility loci.
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| Specifications | |||
|---|---|---|---|
| Number of Fixed Markers | 499,170 | Breast Colorectal Lung Ovarian Prostate |
~120,000 ~40,000 ~45,000 ~50,000 ~80,000 |
| Available Custom Markers, max. | 120,000 | Spacing (kb) | Median 5.4 |
| Number of Samples | 24 | Loss of function | 24,808 |
| DNA Requirement | 200 ng | Insertion/Deletion | 10,208 |
| Assay | Infinium HTS | Exonic ADME SNPs | 4,626 |
| FFPE compatible | Yes | ||
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