Illumina Connected Insights

Streamline oncology clinical research with Illumina Connected Insights

Comprehensive insights and automation to support variant interpretation for diverse applications and variant types at scale

Confidently connect your genomic analysis workflows

The Connected Insights software harnesses extensive knowledge sources via powerful API-integrations for streamlined variant interpretation, including prioritization of relevant clinical trials, drug labels, and guidelines for clinical research. Control over your standardized workflows enables flexibility, and automation speeds your time to relevant insights with procedural consistency. Connected Insights helps you address the interpretation bottleneck and move our understanding of disease forward.

Streamlined

Harness the power of integrated knowledge sources into a single solution to bring insights to diverse applications. Automate your interpretation workflows with customizable presets.

Integrated

Remove unnecessary touchpoints and manual data movement for your NGS workflow, from sequencing through draft report. Seamless and secure, upstream and downstream, directly integrate with the latest DRAGEN secondary analysis.

Powered for growth

Keep pace with comprehensive test options that enable diverse variant and biomarker analyses. Expand assay applications and scale volume without increasing headcount and interpretation resources.

We help you achieve

Insights

Generate insights from 55+ knowledge sources including the Clinical Knowledgebase (CKB) from Genomenon, CiVIC, and OncoKB.

Private curation

Grow and manage your lab's private curated knowledge.

Automation

From data upload, automated guidelines-based oncogenicity classification, to report generation – configure your settings and automate for a streamlined experience with minimum touchpoints.

Future-proofing

Evolve with confidence across assays and applications—from panels to genomes and transcriptomes, from tissue to liquid biopsy and heme.

Regionality

Configure regional content, preferences and language to meet regional needs.

Security

Employ security-first infrastructure and conform to privacy and compliance software requirements and regulations.

Key applications

DNA variants

Identify key DNA variant types (SVs, MNVs, exon-level CNVs, indels, fusions, tandem repeats, LOH) relevant in multiple disease types and across a variety of NGS assays.

RNA variants

Analyze variants from RNA or transcriptomics (fusions, splice variants, and soon expression levels) to gain a deeper and more comprehensive understanding of malignancies.

Biomarker signatures

Uncover more insights by interpreting genome- wide pan-cancer biomarker signatures (TMB, MSI, HRD) with increasing relevance to precision medicine.

NGS workflow with Illumina Connected Insights

Rapid, interpretable data for meaningful insights

Prep

Prepare libraries for somatic oncology panels, CGP, or other compatible applications.

Sequence

Sequence libraries using any Illumina or other sequencing platform.

Analyze

Call variants with DRAGEN or other secondary analysis tools to generate VCF (Variant Call Format) output.

Interpret

Ingest VCF files to Connected Insights to enable generation of insights and case reporting.

Unlock insights with NGS tertiary analysis software

Tertiary analysis software can help address the bottleneck for somatic oncology variant interpretation. Learn key considerations and best practices for implementing a streamlined workflow.

High standards of data privacy and protection

To meet the most stringent security requirements, Illumina Connected Insights platform is built with security and compliance at its core. Read the security brief for more details.

Flexible deployment options

Variant interpretation within a secure cloud ecosystem

The Connected Insights cloud platform directly integrates within an Illumina Connected Software ecosystem, unifying highly scalable data management and processing with enterprise-level data privacy and security features all within a single environment. A direct integration option with DRAGEN for variant calling is seamless and automated.

Variant interpretation on-premises via a local DRAGEN server

The Connected Insights on-premises supports customers in environments where access to the cloud is not an option, offering a solution for local variant calling and interpretation for somatic oncology applications. Accessed via a DRAGEN server, users can directly pair DRAGEN secondary analysis with Connected Insights.

Read about the joint power of DRAGEN and Connected Insights-Local:

Illumina Connected Insights Dragen Brochure
Brochure PDF 1 MB

Highlights

Workflow configuration options

Configure once with a fine level of granularity to match your lab’s standard operating procedure (SOP). Accelerate your workflow by leveraging automation configured according to your SOP.

Lab curation

Grow your lab’s private knowledge base with every case and instantly interpret cases against your historical experience. Your curated knowledge is private, secure, and always at your fingertips.

Streamlined reporting

Customize based on lab name, lab branding, sections, fields, and more. Easily edit reports without data reingestion. Export reports to a chosen language.

Software preview

Save time with automated data upload after one-time configuration. Enjoy workflows with no touchpoints from Illumina sequencers.

Quickly view key findings, coverage, and QC summary in a consolidated format. Intuitively access deeper evidence sources with a streamlined user interface design.

Accelerate turnaround time by automating your exact SOP from variant QC and prioritization to interpretation and reporting by configuring disease, guideline, and lab-specific settings.

Deepen your insights with cutting-edge visualizations –explore genome view, DNA and RNA coverage plots, variant allele frequency (VAF), fusion plots, and more.

Product content and related resources

Illumina Connected Insights brochure

Discover how the Connected Insights can streamline user-defined variant interpretation research workflows and reduce the time it takes to generate meaningful insights, all with a single-vendor workflow.

Download brochure

Illumina Connected Insights video

Watch this video to understand how the Connected Insights can connect various knowledge sources to streamline data interpretation operations for critical insights.

Illumina Connected Insights data sheet

Read how Connected Insights streamlines, integrates, and powers molecular laboratories for scale and growth.

Connected Insights data sheet

Connecting knowledge to clinical data at scale

Key opinion leaders discuss the ongoing challenges and future potential of NGS in clinical oncology.

View article

Illumina Connected Insights security brief

Learn how Connected Insights employs key security and privacy features to protect sensitive NGS data.

Connected Insights security brief

Ready to connect with a genomic scientist?

Discuss your workflow to learn how you can streamline your NGS operations and power your lab for growth using Illumina Connected Insights.

For every lab, everywhere

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Bringing Greater Insights, Answers, and Breakthroughs to Light

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For every lab, everywhere

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For every lab, everywhere

For every lab, everywhere

For every lab, everywhere

For every lab, everywhere

For every lab, everywhere

For every lab, everywhere

For every lab, everywhere

For every lab, everywhere

Illumina Connected Insights

Confidently connect your genomic analysis workflows

Streamlined

Integrated

Powered for growth

We help you achieve

Insights

Private curation

Automation

Future-proofing

Regionality

Security

Key applications

DNA variants

RNA variants

Biomarker signatures