NextSeq 1000 and NextSeq 2000 Innovation and Expertise

Gain momentum with the most trusted benchtop sequencers

Confidently bring NGS to your lab with proven technology and support

scientist starting sequencing run on NextSeq 2000

Innovations that empower researchers across the globe

Illumina is committed to upholding a proven track record of solutions that empower researchers to advance and accelerate their sequencing. That’s why we have invested billions into our research and development and infrastructure to ensure we can equip you with what you need to succeed.

When you partner with Illumina, you’ll get more than just leading-edge technology–you become part of a community with like-minded goals.

female scientist sequencing with NextSeq 2000

Inspiring bold discoveries with global expertise

Our pursuit of innovation continues to inspire scientists to join our growing genomics community, and our proven performance has contributed to Illumina being cited more than any other sequencing company.

421,000+ Sequencing publications
9500+ Customers served
25,000+ Instruments installed
3300+ Trainings per year
15+ Illumina Solution Centers
650+ Support personnel
150+ Countries served
> $1B in R&D investment

Find community and get comprehensive support at every step

Illumina provides a wide range of global, in-language support including remote technical support 24/5, onsite training, instrument qualification and customized onboarding solutions. Because of this, 9 out of 10 customers find it easy to do business with our team.

Get comprehensive support

  • 96% customer satisfaction
  • 97% of calls answered in <30 seconds
  • <1 day mean time to repair
  • 2-day average FSE response time

Connect with fellow innovators

Become a part of a community advancing science together by leading the latest advancements in research and sharing best practices.

Explore Illumina collaborations

Illumina partnerships are expanding access to NGS, pioneering new applications and technologies, providing funding for innovative startups, and more.

Advance your research with streamlined, sustainable benchtop sequencing

Streamline your workflows

Lessen time-to-insight with simple workflows from library prep to data analysis.

Sequence sustainably

Reduce your environmental footprint with sustainable solutions.

Join thousands of researchers who have simplified their sequencing

NextSeq 1000 and NextSeq 2000 Sequencing Systems are flexible and scalable, empowering scientists to explore current and emerging applications like single cell, whole exome, and RNA sequencing. These easy-to-use systems feature an improved user experience with simplified run setup, minimal touchpoints, and flexible informatics solutions, including onboard DRAGEN. The breakthrough system design uses integrated reagent cartridges to minimize waste volume and improve recyclability.

NextSeq 2000 left facing render

See how Illumina benchtop sequencers can transform your lab—today

With the help of the NextSeq 2000, Jun Xia, PhD and Yusi Fu, PhD of Creighton University developed highly accurate single-cell sequencing methods to detect cancer biomarkers. Hear how the NextSeq 2000 fast-tracked their research, opening doors with collaborators to better understand the fundamental processes that drive cancer.

Make your most ambitious research a reality with NextSeq 1000 and NextSeq 2000 innovations

  • <10 minute interface setup with local, cloud, or hybrid run setup
  • 14 different flow cell configurations supporting a wide range of applications
  • Compatibility with a broad range of library prep solutions
  • Dry instrument design and integrated single cartridge for streamlined maintenance, optimized instrument up-time, and minimal waste
NextSeq 1k / 2k development timeline

Empowering even more discoveries with XLEAP-SBS chemistry

Experience our fastest, highest quality, and most robust sequencing by synthesis chemistry, now on the NextSeq 1000 and NextSeq 2000 Systems.

Using the NextSeq 2000 instrument has put our laboratory [into] a completely different league. The higher throughput and faster turnaround time made it possible for us to generate our results and reports much faster and [in] a more comprehensive way.

Dr Csaba Bodor

Semmelweis University, Hungary

NextSeq 1000 and NextSeq 2000 have integrated, onboard analysis–at no extra cost

With the NextSeq 1000 and NextSeq 2000 onboard DRAGEN software, labs can reduce the need for additional computing infrastructure and bioinformatics resources. And with decreased data analysis complexity, researchers can efficiently find key insights in large data sets.

  • 3x reduction in touchpoints for analysis data with BaseSpace

  • 6x faster on-board secondary analysis than Local Run Manager

  • 10+ pipelines that support a wide variety of experiment types

  • 80% less energy for a more sustainable workplace

  • Up to 5x decrease in data footprint possible with ORA Compression

Hear from the scientific community


  1. Internal data on file. Illumina, Inc., 2022

Speak to a specialist about choosing Illumina for your benchtop sequencer

Get in touch to find out how Illumina benchtop sequencing can support your research efforts.