Comparison Table

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  AmpliSeq for Illumina BRCA Panel TruSight Cancer
Key Use Germline and somatic analysis of BRCA1 and BRCA2. Germline mutation detection for common and rare cancers.
Design All exonic regions of the BRCA1 and BRCA2 tumor supressor genes and flanking intronic sequences. Fixed set of probes that enrich for 94 genes and 284 SNPs associated with common and rare cancers.
Library Prep Time 6 hours 12 hours
Genomic Content 22 kb 225 kb (94 genes, 284 SNPs)
Input Amount 10ng recommended 50ng gDNA
FFPE Compatible Yes No
Multiplexing Up to 96-plex Up to 96-plex
Method Amplicon  Enrichment