Strong Demand Drives Book-to-Bill to 1.1    
    SAN DIEGO--(BUSINESS WIRE)--Apr. 2, 2012--      Illumina, Inc. (NASDAQ:ILMN) today announced estimated first quarter      revenue of approximately $270 million. This number is based on a      preliminary estimate and remains subject to review by Illumina’s      independent registered public accounting firm. Analysis of the remainder      of the income statement is incomplete, but the company expects non-GAAP      EPS to be at or above current consensus estimates. Full quarterly      results will be announced later this month.    
      "We are very pleased with our preliminary revenue results and the      ability of the company to focus and execute this quarter. This is our      third consecutive quarter with a book-to-bill over 1, and we are very      encouraged by evidence that our customers are getting back to work,"      said Jay Flatley, President & CEO of Illumina. "Our annualized HiSeq      consumable pull-through grew to approximately $300,000 per instrument in      Q1, a very encouraging trend."    
      Use of forward-looking statements    
      This release contains projections, information about our financial      outlook, earnings guidance, and other forward-looking statements that      involve risks and uncertainties. These forward-looking statements are      based on our expectations as of the date of this release and may differ      materially from actual future events or results. Among the important      factors that could cause actual results to differ materially from those      in any forward-looking statements are (i) our ability to develop and      commercialize further our sequencing, array, PCR, and consumables      technologies and to deploy new products and applications, and expand the      markets, for our technology platforms; (ii) our ability to manufacture      robust instrumentation and consumables; (iii) our expectations and      beliefs regarding future conduct and growth of the business and the      markets in which we operate; (iv) challenges inherent in developing,      manufacturing, and launching new products and services; (v) business      disruptions associated with the tender offer commenced by CKH      Acquisition Corporation, a wholly owned subsidiary of Roche Holding Ltd;      (vi) our ability to maintain our revenue and profitability during      periods of research funding reduction or uncertainty and adverse      economic and business conditions, including as a result of slowing      economic growth in the United States or worldwide, together with other      factors detailed in our filings with the Securities and Exchange      Commission, including our most recent filings on Forms 10-K and 10-Q, or      in information disclosed in public conference calls, the date and time      of which are released beforehand. We undertake no obligation, and do not      intend, to update these forward-looking statements, to review or confirm      analysts’ expectations, or to provide interim reports or updates on the      progress of the current financial quarter.    
      About Illumina    
      Illumina (www.illumina.com)      is a leading developer, manufacturer, and marketer of life science tools      and integrated systems for the analysis of genetic variation and      function. We provide innovative sequencing and array-based solutions for      genotyping, copy number variation analysis, methylation studies, gene      expression profiling, and low-multiplex analysis of DNA, RNA and      protein. We also provide tools and services that are fueling advances in      consumer genomics and diagnostics. Our technology and products      accelerate genetic analysis research and its application, paving the way      for molecular medicine and ultimately transforming healthcare.    
      ADDITIONAL INFORMATION AND WHERE TO FIND IT    
      This communication does not constitute an offer to buy or a solicitation      of an offer to sell any securities. In response to the tender offer      commenced by CKH Acquisition Corporation, a wholly owned subsidiary of      Roche Holding Ltd, Illumina has filed a solicitation/recommendation      statement on Schedule 14D-9 with the SEC. INVESTORS AND SECURITY HOLDERS      OF ILLUMINA ARE URGED TO READ THE SOLICITATION/RECOMMENDATION STATEMENT      AND OTHER DOCUMENTS FILED WITH THE SEC (WHEN THEY BECOME AVAILABLE)      CAREFULLY IN THEIR ENTIRETY BECAUSE THEY CONTAIN IMPORTANT INFORMATION.      Investors and security holders are able to obtain free copies of these      documents and other documents filed with the SEC by Illumina (when they      become available) through the web site maintained by the SEC at http://www.sec.gov.      Investors and security holders also are able to obtain free copies of      these documents, and other documents filed with the SEC by Illumina      (when they become available), from Illumina by directing a request to      Illumina, Inc., Attn: Investor Relations, Kevin Williams, MD, kwilliams@illumina.com.    
      In addition, in connection with its 2012 Annual Meeting of Stockholders,      Illumina has filed a definitive proxy statement and a WHITE proxy card      with the SEC on March 19, 2012, and has mailed the definitive proxy      statement and WHITE proxy card to its security holders. INVESTORS AND      SECURITY HOLDERS OF ILLUMINA ARE URGED TO READ THE DEFINITIVE PROXY      STATEMENT AND THE WHITE PROXY CARD FOR THE 2012 ANNUAL MEETING OF      STOCKHOLDERS AND OTHER DOCUMENTS FILED WITH THE SEC (WHEN THEY BECOME      AVAILABLE) CAREFULLY IN THEIR ENTIRETY BECAUSE THEY CONTAIN IMPORTANT      INFORMATION. Investors and security holders are able to obtain free      copies of the definitive proxy statement and other documents filed with      the SEC by Illumina (when they become available) through the web site      maintained by the SEC at http://www.sec.gov.      Investors and security holders also are able to obtain free copies of      the definitive proxy statement, and other documents filed with the SEC      by Illumina (when they become available), from Illumina by directing a      request to Illumina, Inc., Attn: Investor Relations, Kevin Williams, MD, kwilliams@illumina.com.    
      CERTAIN INFORMATION REGARDING PARTICIPANTS IN THE SOLICITATION    
      Illumina and certain of its directors and executive officers may be      deemed to be participants in the solicitation of proxies in connection      with Illumina’s 2012 Annual Meeting of Stockholders under the rules of      the SEC. Security holders may obtain information regarding the names,      affiliations and direct and indirect interests (by security holdings or      otherwise) of Illumina’s directors and executive officers in      (i) Illumina’s Annual Report on Form 10-K for the year ended January 1,      2012, which was filed with the SEC on February 24, 2012, and      (ii) Illumina’s definitive proxy statement for its 2012 Annual Meeting      of Stockholders, which was filed with the SEC on March 19, 2012. To the      extent that Illumina’s directors’ and executive officers’ holdings of      Illumina’s securities have changed from the amounts printed in the      definitive proxy statement for the 2012 Annual Meeting of Stockholders,      such changes have been or will be reflected on Statements of Changes in      Beneficial Ownership on Form 4 filed with the SEC. These documents can      be obtained free of charge from the sources indicated above.    

Source: Illumina, Inc.
      Illumina, Inc.
Investors:
Kevin Williams, MD
Investor      Relations
858-332-4989
kwilliams@illumina.com
or
Media:
Jennifer      Temple
Public Relations
858-429-8650
pr@illumina.com