MiSeqDx Cystic Fibrosis 139-Variant Assay

MiSeqDx Cystic Fibrosis 139-Variant Assay

Intended Use The Illumina MiSeqDx Cystic Fibrosis 139-Variant Assay is a qualitative in vitro diagnostic system used to simultaneously detect 139 clinically relevant cystic fibrosis disease-causing mutations and variants of the cystic fibrosis transmembrane conductance regulator (CFTR) gene in genomic DNA isolated from human peripheral whole blood specimens. The variants include those recommended in 2004 by the American College of medical Genetics (ACMG) and in 2011 by the American College of Obstetricians and Gynecologists (ACOG). The test is intended for carrier screening in adults of reproductive age, in confirmatory diagnostic testing of newborns and children, and as an initial test to aid in the diagnosis of individuals with suspected cystic fibrosis. The results of this test are intended to be interpreted by a board-certified clinical molecular geneticist or equivalent and should be used in conjunction with other available laboratory and clinical information.

This test is not indicated for use for newborn screening, fetal diagnostic testing, pre-implantation testing, or for stand-alone diagnostic purposes.

This test is intended to be used on the Illumina MiSeqDx instrument.

Catalog IDs:

  • DX-102-1003

    Library prep reagents for up to 960 samples

    MiSeqDx sequencing reagents for 20 runs with a maximum of 48 samples per run

  • DX-102-1004

    Library prep reagents for up to 96 samples

    MiSeqDx sequencing reagents for 2 runs with a maximum of 48 samples per run

Additional parts:

  • FC-130-1005 TruSeq Index Plate Fixture Kit
  • FC-130-1007 TruSeq Index Plate Fixture & Collar Kit