The NovaSeq 6000 Sequencing System is designed to adapt to your needs. This robust, scalable system has been adopted by leading research centers and featured in countless publications. Impactful discoveries are within reach.Contact an Illumina Representative
So many ways to sequence. Scale up and down with a tunable output of up to 6 Tb and 20B single reads in < 2 days.
Accelerate your science with reliable sequencing breadth and depth for every project.
Do what you want. Mix and match flow cell types, and run one or two flow cells at a time. Choose between multiple read lengths, workflows, and more.
The NovaSeq 6000 system offers deep and broad coverage through advanced applications for a comprehensive view of the genome. Unlock a full spectrum of genetic variation and biological function with high-throughput sequencing.See All Applications
Manage your workflow seamlessly with BaseSpace Clarity LIMS or your existing LIMS system.
Prepare libraries with a broad range of high-performance library preparation kits.
Generate sequences with ready-to-use reagents featuring proven Illumina sequencing by synthesis chemistry.
Leverage the Illumina DRAGEN Bio-IT Platform or BaseSpace Sequence Hub for accurate, rapid secondary analysis.
Interpret results, get insights, and drive discovery with BaseSpace Variant Interpreter, and TruSight Software Suite.
|NovaSeq 6000 System||NovaSeq X Series|
|Run Time:||~13 hr - ~44 hr||~13 hr - ~48 hr|
|Maximum Output:||6 Tb||16 Tb (for NovaSeq X Plus system)|
|Maximum Reads per Run:||20 billion single-end reads; 40 billion paired-end reads||52 billion single-end reads; 104 billion paired-end reads (for NovaSeq X Plus system)|
|Maximum Read Length:||2 x 250 bp||2 x 150 bp|
|Key Applications:||Whole-genome sequencing
|DRAGEN Data Analysis Offerings:||(on-premise or cloud)
|Featured Products:||NovaSeq 6000 Reagent Kits
NovaSeq XP Workflow
Illumina RNA Prep with Enrichment
Illumina DNA PCR-Free Prep
Illumina Complete Long Read Prep, Human
|Novaseq X Series Reagent Kits
Illumina DNA PCR-Free Prep
Illumina DNA Prep with Enrichment
Illumina Stranded Total RNA Prep
Probe deeper into a single sample for insights or process more samples to improve statistical signficance.
Perform transformative science with access to multiple emerging high-throughput omics applications.
Long-read sequencing enables the sequencing of much longer DNA fragments than traditional short-read sequencing methods.
New kits feature updated reagent formulations with 2x longer shelf life and improved sequencing costs to help power your most impactful studies.
The NovaSeq 6000 Xp workflow enables labs to load libraries directly into each lane of a NovaSeq 6000 system flow cell, without additional instrumentation.
Achieve rapid, targeted interrogation of an expansive number of target genes with exceptional capture efficiency and coverage uniformity.
A high-performing, fast, and integrated workflow for sensitive applications such as human whole-genome sequencing.
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See what’s possible with the proven NovaSeq 6000 system and NGS technologySee All Stories
Rady Children’s Institute for Genomic Medicine is using the DNA PCR-Free Prep kit for NovaSeq 6000 to make a potentially record-breaking time-to-diagnosis for children with rare genetic disordersRead More
Cole Trapnell, PhD is transforming the world of biology by making bioinformatics tools available to allRead More
OmniSeq, Inc. scaled up to process a large number of both tissue and blood plasma samples every week, batching from 16 to 192 samples in a single run on the NovaSeq 6000Read More
Genomics England’s human genome initiative (GenOMICC) has launched a study aimed at uncovering genetic factors in susceptibility to COVID-19Read More
The DRAGEN platform enables GeneDx to scale to whole-genome analysis and identify variants with precisionRead More