DRAGEN secondary analysis deployment options

Flexible configurations enable researchers to access DRAGEN analysis via on-premises server, in the cloud, or on-instrument

Multiplatform accessibility

Multiplatform accessibility

Depending on your NGS data analysis needs and preferences, DRAGEN secondary analysis can be launched via on-premises server, in the cloud, or directly onboard the NextSeq 1000 and NextSeq 2000 Sequencing Systems and the NovaSeq X Series.

Current DRAGEN analysis deployment options

Deployment option Description Related info
DRAGEN server

An on-premises option is available via a DRAGEN server that offers highly accurate secondary analysis in a fraction of the time compared with a traditional CPU-based system.

The DRAGEN server:

  • Analyzes and stores data locally
  • Supports command line interface (CLI)
  • Replaces up to 30 traditional open source tools1
  • Offers high configurability, update frequency, and pipeline options
Integrating Illumina DRAGEN secondary analysis within your infrastructure (tech note)
DRAGEN analysis on Illumina managed cloud

DRAGEN secondary analysis can be deployed on the cloud via Illumina Connected Analytics or BaseSpace Sequence Hub:

  • DRAGEN on Connected Analytics couples the accuracy and speed of DRAGEN secondary analysis with the ability to customize analysis pipelines and operationalize informatics on a secure platform
  • DRAGEN on BaseSpace Sequence Hub (BSSH) provides push-button analysis capabilities in an intuitive, easy-to-use interface with the secure compliance and data storage features of BaseSpace Sequence Hub

Connected Analytics data sheet

DRAGEN on BaseSpace Sequence Hub data sheet

Learn more about the following Illumina cloud platforms:

Connected Analytics

BaseSpace Sequence Hub

DRAGEN analysis onboard

DRAGEN secondary analysis is available onboard the NovaSeq X Series and NextSeq 1000 and NextSeq 2000 Systems at no extra cost. Deploying DRAGEN onboard provides exceptionally fast, accurate, and comprehensive secondary analysis without investing in additional computing infrastructure or bioinformatics resources.



Onboard NextSeq 1000 and NextSeq 2000 Systems

Seamlessly integrate sequencing and analysis functions with versatile analysis pipeline options, including single-cell, exome, and RNA analysis. 

  • Simplify your workflow with an easy-to-use graphical interface and fewer touchpoints
  • Generate high-quality analysis
  • Get results in as little as two hours

DRAGEN onboard NextSeq 1000 and NextSeq 2000 data sheet

View NextSeq 1000 and NextSeq 2000 Systems


Onboard NovaSeq X Series

Flexibly run multiple secondary analysis pipelines in parallel. Access DRAGEN BCL Convert, Germline, somatic (tumor only), Enrichment, methylation and RNA pipelines.

  • Run up to four simultaneous applications per flow cell in a single run
  • Achieve up to 5× lossless data compression and analysis with supported applications
  • Save on analysis costs, which can exceed the cost of the sequencing system over five years2*

NovaSeq X Series software ecosystem tech note

View NovaSeq X Series

*Assuming 10,000 WGS per year for NovaSeq X System and 20,000 WGS per year for NovaSeq X Plus System

DRAGEN for IVD applications

DRAGEN can be deployed on servers paired with select Illumina Dx sequencing systems for IVD applications.

DRAGEN server for the NovaSeq 6000Dx Instrument

The NovaSeq 6000Dx system includes a DRAGEN Server paired with the sequencer, enabling streamlined and accurate data analysis. The intuitive software interface makes it easy to maximize your analysis efficiency. 

For In Vitro Diagnostic Use only.

Learn more or get in touch

View more details about DRAGEN analysis features, learn how to order, and find product documentation. You can also speak to a specialist to get your questions answered.

  1. Data calculations on file. Illumina, Inc. 2022.
  2. Illumina Internal Data on File, 2023.