The long sort of short: new insights into haplotype phasing with Illumina TruPath™ Genome

Overview

Accurate haplotype phasing is critical for interpreting complex genomic variation and remains challenging with conventional short‑read sequencing alone. In this webinar, Mitch Bekristky (Associate Director Bioinformatics) will explain how Illumina TruPath™ Genome uses proximity mapped read technology to deliver long‑range information from short‑read data, benchmarked against long‑read approaches.

Tim A. Steiert, PhD, from the Institute of Clinical Molecular Biology Kiel, Germany will then present how Illumina TruPath™ Genome delivers long‑range information from short‑read data in complex blood group loci and how this compares to long-read technologies.

What you’ll learn

• How proximity mapped read technology enables long‑range insights from short reads
• Capability of TruPath Genome to resolve challenging blood group loci
• Practical advantages of TruPath Genome, including automation and low DNA input requirements 

Mitchell Bekritsky
Associate Director, Bioinformatics, Illumina

Tim A. Steiert, PhD
Postdoctoral Researcher, Competence Centre for Genome Analysis Kiel (CCGA), Germany

Tim A. Steiert, PhD, is a postdoctoral researcher at the Competence Centre for Genome Analysis Kiel (CCGA), Germany, where his work focuses on next‑generation sequencing methods for immunohematology and blood group genomics. He specialises in developing and benchmarking laboratory and bioinformatic approaches to improve the accuracy and scalability of blood group genotyping.

M-GL-04353