This sequencing research panel assesses germline variants in 11 genes associated with inherited breast and ovarian cancers.
This panel was developed as a research method to identify genetic mutations associated with inherited breast and ovarian cancers. The panel assesses 11 genes known to harbour mutations related to breast and/or ovarian cancer (ATM, BRCA1, BRCA2, CHEK2, PALB2, RAD51C, RAD51D, NBN, CDH1, SMARCA4, and TP53).
AmpliSeq for Illumina Community Panels are made-to-order. We provide the designs for your convenience; however, they do not have associated performance metrics. For predesigned and tested content, view AmpliSeq for Illumina Ready-to-Use Panels.
AmpliSeq for Illumina Community Panels contain content selected and designed with input from leading disease researchers. You can order this community panel as is, or customize the panel to meet your needs, using DesignStudio software to add or remove genes and amplicons.
| Input quantity | 1–100 ng; recommended 10 ng per pool |
|---|---|
| Method | Amplicon sequencing |
| Nucleic acid type | DNA |
| Number of amplicons | 699 total (3 pools of 233 amplicons each). |
| Species category | Human |
| Technology | Sequencing |
In addition to the community panel, you will also need an AmpliSeq Library PLUS kit and index adapters.
AmpliSeq™ BRCA Plus, Extended Hereditary Breast and Ovarian Research Panel for Illumina®
20020495
Custom assay supporting 750 or 3000 samples with < 4999 amplicons. Purchase Library PLUS and index adapters separately.
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Advanced chemistry, optics, and informatics combine to deliver exceptional speed and data quality, outstanding throughput and scalability.
Optimized reagent kit that provides increased cluster density and read length, improving sequencing quality scores compared to earlier versions.
Enable CGP with a large pan-cancer panel covering all major variant classes plus gene signatures (TMB, MSI, and HRD) from FFPE tissue.
A fast, integrated workflow for preparing libraries for use in a wide range of sequencing applications.
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