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The Infinium Multi-Ethnic Global-8 Kit provides a true multi-purpose, multi-ethnic genotyping array. With > 1.7 million expertly selected markers, it enables identification of genetic associations with common and rare traits, providing insight across diverse populations to epidemiologists, health care researchers, population geneticists, and genomic researchers.
This kit combines expertly selected markers and content from the most popular Illumina commercial arrays with the most current genomic information. Researchers can detect both common and rare variants across the most commonly studied 5 major super-populations and impute variants in a vast number of subpopulations.
Consortium partners developed content for this multi-ethnic global genotyping array using tagging strategies with the power to perform more effective association studies in diverse populations. The novel algorithm selects population-specific and transethnic tag SNPs that maximize imputation accuracy, as imputation has become a standard practice in the interpretation of genotyping data and allows for more accurate statistical inference of genotypes not directly genotyped.
| Infinium Multi-Ethnic Global-8 Kit | Infinium Omni2.5-8 Kit | Infinium Omni5-4 Kit | |
|---|---|---|---|
| Description | With content from a variety of resources, this multiethnic array allows researchers to detect both common and rare variants across the most commonly studied 5 superpopulations in order to impute variants in a vast number of subpopulations. | 8-sample arrays with high throughput and optimized tag SNP content, including full support of copy number variation applications, designed to be highly customizable and maximally informative for studying diverse world populations. | A high-density array that provides exceptional coverage of common, intermediate, and rare SNPs while leveraging powerful tag SNPs and offering optimized content for whole-genome genotyping and copy number variation studies. |
| Number of Markers | Fixed markers: 1,779,819 Custom marker add-on capacity: Up to 245,000 |
Fixed markers: ~2,380,000, Custom marker add-on capacity: None | Fixed markers: 4,284,426, Custom marker add-on capacity: None |
| Number of Samples | 8 samples per array | 8 samples per array | 4 samples per array |
| Sample Throughput | ~1067 samples per week (estimate for 1 HiScan System, 1 AutoLoader 2.x, 1 Tecan robot, and a 5-day work week) | ~1067 samples per week (estimate for 2 iScan Systems, 1 AutoLoader 2.x, 2 Tecan robots, and a 5-day work week) | >460 samples per week (estimate for 2 iScan Systems, 1 AutoLoader 2.x, 3 Tecan robots, and a 5-day work week) |
| Species Category | Human | Human | Human |
Custom Cluster File Creation for Improved Copy Number Analysis
Technical Note | PDF< 1 MB
Infinium Multi-Ethnic Global BeadChip
Data Sheet | PDF< 1 MB
Infinium Assay Lab Setup and Procedures Guide Documentation
Best Practices for Infinium Assays Documentation
Infinium LCG Assay Automated Protocol Experienced User Card (15023141) Documentation
Illumina Infinium LCG Assay Manual Protocol Experienced User Card (15023140) Documentation
Infinium Multi-Ethnic Global-8 Kit Documentation
Infinium LCG Assay Lab Tracking Form (15023142) Documentation
Microarrays are a valuable tool for variant detection. With the Gene Panel and Array Finder, you can search human microarrays by genomic location or variant ID, or find arrays for other species.
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The Infinium ImmunoArray-24 v2 BeadChip is the next-generation genotyping array for detecting genetic variation in the immune system.
A cost-effective array for understanding complex disease in diverse human populations, focused on European, East Asian, and South Asian populations.
A cost-effective array for understanding complex disease in diverse human populations, focused on Hispanic and African American populations.
