Infinium Training
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The Infinium Multi-Ethnic Global-8 Kit provides a true multi-purpose, multi-ethnic genotyping array. With > 1.7 million expertly selected markers, it enables identification of genetic associations with common and rare traits, providing insight across diverse populations to epidemiologists, health care researchers, population geneticists, and genomic researchers.
This kit combines expertly selected markers and content from the most popular Illumina commercial arrays with the most current genomic information. Researchers can detect both common and rare variants across the most commonly studied 5 major super-populations and impute variants in a vast number of subpopulations.
Consortium partners developed content for this multi-ethnic global genotyping array using tagging strategies with the power to perform more effective association studies in diverse populations. The novel algorithm selects population-specific and transethnic tag SNPs that maximize imputation accuracy, as imputation has become a standard practice in the interpretation of genotyping data and allows for more accurate statistical inference of genotypes not directly genotyped.
| Infinium Multi-Ethnic Global-8 Kit | Infinium Omni2.5-8 Kit | Infinium Omni5-4 Kit | |
|---|---|---|---|
| Description | With content from a variety of resources, this multiethnic array allows researchers to detect both common and rare variants across the most commonly studied 5 superpopulations in order to impute variants in a vast number of subpopulations. | 8-sample arrays with high throughput and optimized tag SNP content, including full support of copy number variation applications, designed to be highly customizable and maximally informative for studying diverse world populations. | A high-density array that provides exceptional coverage of common, intermediate, and rare SNPs while leveraging powerful tag SNPs and offering optimized content for whole-genome genotyping and copy number variation studies. |
| Number of Markers | Fixed markers: 1,779,819 Custom marker add-on capacity: Up to 245,000 |
Fixed markers: ~2,381,000, Custom marker add-on capacity: None | Fixed markers: 4,284,426, Custom marker add-on capacity: None |
| Number of Samples | 8 samples per array | 8 samples per array | 4 samples per array |
| Sample Throughput | ~1728 samples/week max per iScan (throughput and scan times may vary based on laboratory and system configurations.) | ~1728 samples/week per iScan (max throughput and scan time may vary based on lab and system configurations) | >460 samples per week (estimate for 2 iScan Systems, 1 AutoLoader 2.x, 3 Infinium Automated Pipetting Systems, and a 5-day work week) |
| Species Category | Human | Human | Human |
Infinium Multi-Ethnic Global BeadChip
Data Sheet | PDF< 1 MB
Infinium LCG Assay Reference Guide Documentation
Infinium Assay Lab Setup and Best Practices Documentation
Infinium Assay Consumables and Equipment List Documentation
Infinium LiHa and Infinium RoMa Operating Manual Documentation
Best Practices for Infinium Assays Documentation
Infinium LCG Assay Manual Workflow Checklist Documentation
Infinium LCG Assay Automated Workflow Checklist Documentation
Infinium LCG Assay Lab Tracking Form (15023142) Documentation
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