BeadChip combining exceptional coverage of clinical research variants with optimized multiethnic, genome-wide content for genotype screening.
Sample throughput
Number of samples
Number of markers
The Infinium Global Diversity Array-8 Kit is the recommended replacement for the Infinium Multi-Ethnic Global, Multi-Ethnic AMR/AFR, and Multi-Ethnic EUR/EAS/SAS Kits, which have been discontinued. The Global Diversity Array is an updated version of the Multi-Ethnic Kits.
The Infinium Global Diversity Array 8-Kit (GDA) BeadChip is a powerful, cost-effective array with optimized, multiethnic, genome-wide content.
The GDA is the commercial version of the microarray trusted by this NIH precision medicine initiative, which will collect data from > 1M people to improve health outcomes.
A high-density SNP global backbone for cross-population imputation coverage of the genome enables polygenic risk score development and characterization of genetic architecture in diverse populations.
The robust genome-wide scaffold was designed to tag common and low-frequency variants in global populations through collaborations with the Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA) and Population Architecture using Genomics and Epidemiology (PAGE). Content includes > 1K whole-genome sequences of African ancestry and populations throughout the Americas.
| Assay type | Infinium LCG |
|---|---|
| Automation capability | Automated array loader, Liquid handling robot(s) |
| Description | The 8-sample Infinium Diversity Array provides targeted coverage of more than 4800 key genes across the genome. Approximately 1.8M markers are included on the BeadChip for high exonic coverage in regions of disease relevance, providing highly accurate copy number variation calls, and an average resolution of 1.5Mb. |
| Input quantity | 200 ng |
| Instruments | iScan System |
| Method | Genome-wide genotyping array |
| Nucleic acid type | DNA |
| Number of markers | 1,825,277 fixed markers. Custom marker add-on capacity: Up to 175K. |
| Number of samples | 8 samples per array |
| Sample throughput | 1728 samples per week |
| Specialized sample types | Blood, FFPE tissue, Buccal swabs, Saliva |
| Species category | Human |
| Technology | Microarray |
| Variant class | Single nucleotide polymorphisms (SNPs), Loss of heterozygosity (LOH), Chromosomal abnormalities, Structural variants, Copy number variants (CNVs) |
Advanced chemistry, optics, and informatics combine to deliver exceptional sequencing speed and data quality, outstanding throughput, and scalability.
Optimized reagent kit that provides increased cluster density and read length, improving sequencing quality scores compared to earlier versions.
Enable CGP with a large pan-cancer panel covering all major variant classes plus gene signatures (TMB, MSI, and HRD) from FFPE tissue.
A fast, integrated workflow for preparing libraries for use in a wide range of sequencing applications.
Data calculations on file. Illumina, Inc. March 2021.
The 1000 Genomes Project. 1000 genomes.org. Accessed August 24, 2021.
PharmGKB, The Pharmacogenomics Knowledgebase. www.pharmgkb.org. Accessed August 4, 2021.
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