From discovery to development

An innovative portfolio for drug development

NGS for Drug Development

Illumina provides an innovative portfolio of next-generation sequencing (NGS) systems, products, and services for the drug development pipeline. With solutions to inform the drug development process, you can confidently choose us as a partner from discovery through companion diagnostics development.

NGS approaches can generate multiple levels of genomic data essential for drug development, from genomic modifications to transcriptome profiling and quantification, epigenetic modifications, and more.

We are uniquely positioned to deliver products and services to support pharmaceutical development with the largest install base of next-generation sequencing (NGS) instrumentation.

Approximately 90 percent of all sequencing data produced today has been generated using Illumina technologies*. Reference and service labs are installing our instruments in increasing numbers to perform a wide variety of applications.

* Data calculations on file. Illumina, Inc. 2017

The Illumina portfolio of solutions informs various stages of the drug development process.

Click on the below to view methods and products supporting drug development.

Whole-Genome Sequencing

Take a comprehensive view of the genomic variation linked to a pathway.

Whole-Exome Sequencing

Explore genomic variation in a more cost-effective way.

RNA Sequencing

Characterize expression by sequencing individual targets to the entire transcriptome.

Targeted Cancer Sequencing

Take a deeper view to confirm genomic variation of interest with custom or fixed panels.

TruSight Oncology 500 Product Family

Enabling comprehensive genomic profiling from both blood and tissue samples.

Cancer Immunotherapy Research

NGS methods enable efficient, broad, and deep assessment of tumors and their microenvironment.

Drug Response RNA Biomarker Discovery

Learn how to use RNA-Seq to identify novel RNA-based drug response biomarkers.

Epigenetics

Find NGS and array tools to study epigenetic modifications and their impact on gene regulation.

Sequencing Systems

Find the sequencer that best fits your scale of study.

Microarray Solutions

A complete range of tools and services for every need.

Bioinformatics Tools

Informatics tools to guide you from experimental design to data interpretation and reporting.

Service Providers

Find a service provider through our Propel program to support your genomics needs.

Targeted Cancer Sequencing

Take a deeper view to confirm genomic variation of interest with custom or fixed panels. Detect single-nucleotide variants (SNVs), amplifications, and fusions that contribute to solid tumor progression with TruSight Tumor 170.

TruSight Oncology 500 Product Family

Enabling comprehensive genomic profiling from both blood and tissue samples.

Cancer RNA Sequencing

Confirm expression in transcripts of interest with targeted panels and access hard-to-analyze FFPE samples. Also leverage RNA-Seq to discover and profile RNA-based drug response biomarkers.

Immunotherapy Research

NGS methods enable efficient, broad, and deep assessment of tumors and their microenvironment

Sequencing Systems

Find the sequencer that best fits your scale of study.

Informatics

Bioinformatics tools guide you from experimental design to data interpretation and reporting.

Service Providers

Find a service provider through our Propel program to support your genomics needs.

Targeted Cancer Sequencing

Take a deeper view to confirm genomic variation of interest with custom or fixed panels. Detect single-nucleotide variants (SNVs), amplifications, and fusions that contribute to solid tumor progression with TruSight Tumor 170.

TruSight Oncology 500 Product Family

Enabling comprehensive genomic profiling from both blood and tissue samples.

Cancer RNA Sequencing

Confirm expression in transcripts of interest with targeted panels and access hard-to-analyze FFPE samples. Also leverage RNA-Seq to discover and profile drug response RNA biomarkers.

Immunotherapy Research

NGS methods enable efficient, broad, and deep assessment of tumors and their microenvironment

Sequencing Systems

Find the sequencer that best fits your scale of study.

Informatics

Bioinformatics tools guide you from experimental design to data interpretation and reporting.

Service Providers

Find a service provider through our Propel program to support your genomics needs.

Explore our unique, multi-analyte approach to co-development.

Targeted Cancer Sequencing

Take a deeper view to confirm genomic variation of interest with custom or fixed panels. Detect single-nucleotide variants (SNVs), amplifications, and fusions that contribute to solid tumor progression with TruSight Tumor 170.

TruSight Oncology 500 Product Family

Enabling comprehensive genomic profiling from both blood and tissue samples.

Cancer RNA Sequencing

Confirm expression in transcripts of interest with targeted panels and access hard-to-analyze FFPE samples.

Immunotherapy Research

NGS methods enable efficient, broad, and deep assessment of tumors and their microenvironment.

Sequencing Systems

Find the sequencer that best fits your scale of study.

Companion Diagnostics Development

Explore our unique, multi-analyte approach to co-development.

High-Throughput Genotyping Research Tools

Gain meaningful insights from complex populations.

Informatics

Bioinformatics tools guide you from experimental design to data interpretation and reporting.

Service Providers

Find a service provider through our Propel program to support your genomics needs.

Companion Diagnostic Development

Explore our unique, multi-analyte approach to co-development.

MiSeqDx Instrument

Discover the first FDA-cleared next-generation sequencing system.

NextSeq550Dx Instrument

Explore the next level in diagnostic power for the clinical lab.

High-Throughput Genotyping Research Tools

Gain meaningful insights from complex populations.

Service Providers

Find a service provider through our Propel program to support your genomics needs.

Exclusive Offer for TruSight Oncology 500

Purchase the TruSight Oncology 500 assay for the first time and receive an exclusive limited time offer.

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Exclusive Offer for TruSight Oncology 500

Featured Drug Discovery and Development Articles

GLOBAL Clinical Study Demonstrates Value of Panomics-Based Drug Discovery Approach
Value of a Panomics-Based Drug Discovery Approach

Integrating imaging, multiomic technologies, and big data uncovers novel diagnostic and therapeutic targets for common chronic diseases.

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Tumor
Beyond Single-Drug Approaches to Precision Oncology

Researchers utilize transcriptomics to uncover multiple drug-susceptible tumorigenic pathways.

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The Time is Now for Microbiome Studies
The Time is Now for Microbiome Studies

Whole-genome shotgun sequencing and transcriptomics provide researchers and pharmaceutical companies with data to refine drug discovery and development.

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Cancer
Cancer Research

NGS-based methods allow cancer researchers to detect rare somatic variants, tumor subclones, and circulating DNA fragments. Learn more about cancer genomics.

Microbiology
Microbial Sequencing

From metagenomics and microbiome studies to infectious disease surveillance, NGS can help researchers gain genetic insight into bacteria and viruses. Learn more about microbial genomics.

Complex Diseases
Complex Disease Research

Sequencing is introducing new avenues for understanding autoimmune and rheumatic diseases, atherosclerosis, neurological disorders, and psychiatric disorders on a molecular level. Learn more about complex disease genomics.

Rare Diseases
Rare disease researchers pipetting

NGS can help scientists uncover genetic variants associated with rare and undiagnosed disorders. Learn more about rare disease genomics.

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NGS Used for Biological QC in BioPharma Production
NGS Used for Biological QC in BioPharma Production

Read how Merck Serono uses NGS for cell line stability testing and biosafety monitoring.

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Polygenic Risk Scores
Polygenic Risk Scores

Polygenic risk scores represent the total number of genetic variants that an individual has to assess their heritable risk of developing a particular disease.

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