This panel was developed as a quick, accurate, and cost-effective research method to identify genetic variants associated with early onset dementia. The panel assesses 17 genes known to harbor variants linked to dementia (PRNP, PSEN1, PSEN2, APP, GRN, MAPT, TREM2, CHMP2B, CSF1R, FUS, ITM2B, NOTCH3, SERPINI1, TARDBP, TYROBP, VCP, and SQSTM1). This panel contains 214 amplicons in 2 pools.
AmpliSeq for Illumina Community Panels are made-to-order. We provide the designs for your convenience; however, they do not have associated performance metrics. For predesigned and tested content, view AmpliSeq for Illumina Ready-to-Use Panels.
AmpliSeq for Illumina Community Panels contain content selected and designed with input from leading disease researchers. You can order this community panel as is, or customize the panel to meet your needs, using DesignStudio software to add or remove genes and amplicons.
In addition to the community panel, you will also need an AmpliSeq Library PLUS kit and index adapters.
Dementia.dna_manifest.20171207.zip
manifest_file | ZIP < 1 MB
AmpliSeq for Illumina Custom and Community Panels Documentation
Custom Protocol Selector
Generates customized, end-to-end instructions
All AmpliSeq for Illumina Custom and Community Panels Support