Illumina technology can advance immunology research by helping elucidate immune cell function and signaling. Immune cells work to protect the body from foreign invaders including viruses, bacteria, and parasites. Mutations and environmental factors can cause the immune system to malfunction and attack the body it is meant to protect. Many immune disorders are classified as complex diseases since they are influenced by both genetics and the environment.
Complex autoimmune disorders include lupus, rheumatoid arthritis, inflammatory bowel disease, and others. The cause and progression of many of these diseases are still not understood.
Array and next-generation sequencing (NGS) solutions from Illumina can provide immunology researchers with detailed insight into the potential genetic causes and functional consequences of variation.
AmpliSeq for Illumina Immune Repertoire Plus, TCR beta Panel: Investigate T cell diversity and clonal expansion by sequencing T cell receptor beta chain rearrangements.
Infinium ImmunoArray-24 v2 BeadChip Kit: Perform research to evaluate autoimmune disorder and immune function–associated genetic variants on a single array.
NGS can help researchers identify mutations that enable tumors to evade the immune response, as well as neoantigens that can boost T cell-mediated immunity.
A reproducible, economical method for sequencing coding RNA, including FFPE samples. View Kit.See All RNA-Seq Solutions
Flexible desktop sequencing systems that support various applications, from targeted panels to whole-genome sequencing. Learn More.See All Sequencers