Respiratory Pathogen ID/AMR Enrichment Panel Kit (Powered by IDbyDNA Explify)

This NGS panel targets >280 respiratory pathogens (including SARS-CoV-2) and 1200+ antimicrobial resistance alleles, with data analysis powered by IDbyDNA. Read More...
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Respiratory Pathogen ID/AMR Enrichment Kit Set A (RUO) (96 indexes, 96 samples)

20047050

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Respiratory Pathogen ID/AMR Enrichment Kit Set B (RUO) (96 indexes, 96 samples)

20046969

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Product Highlights

The Respiratory Pathogen ID/AMR Enrichment Kit is a next-generation sequencing (NGS)-based respiratory pathogen panel that delivers highly sensitive, comprehensive pathogen detection and antimicrobial resistance (AMR) insights. The enrichment panel targets >280 respiratory pathogens, including SARS-CoV-2 and other viruses, bacteria, and fungi, and 1200+ AMR alleles.

Powered by IDbyDNA Explify Analysis Software, the flexible and scalable end-to-end workflow, coupled with broad identification of respiratory pathogens and AMR alleles in <24 hours, delivers a rapid, cost-effective solution for detecting respiratory tract infections in clinical research settings.

Features of this workflow:

  • Universal Detection of Respiratory Pathogens — Delivers comprehensive detection of critical pathogens, including SARS-CoV-2. The respiratory pathogen panel (RPIP) simultaneously detects RNA and DNA for 180+ bacteria, 50+ fungi, and 40+ viruses.
  • Detection of Antimicrobial Resistance Genes — Accurate prediction of resistance of 16 common respiratory pathogens to 60 relevant antimicrobials based on detection of > 1200 associated AMR markers
  • Strain Typing of Critical Pathogens — Report full genome coverage of SARS-CoV-2 and Influenza A/B viruses to surveil new variants and lineages
  • Quality Control — Includes probes targeting 10 commercially available spike-in control options.
  • Cost-Effective — The comprehensive respiratory pathogen panel design enables cost-effective detection of RNA and DNA respiratory pathogens and antimicrobial resistance alleles all at the same time, from the same assay.
  • Rapid – Delivers simultaneous detection of bacteria, viruses, fungi, and AMR alleles in <24 hours using the MiniSeq Rapid Reagent Kit.

Powerful, Simple Data Analysis with the IDbyDNA Explify Platform

The IDbyDNA Explify RPIP Analysis App offers a paired and tailored data analysis solution for the Illumina Respiratory Pathogen ID/AMR Enrichment Kit. The app provides information on sample composition, including host and microbial abundance, and proportion of targeted vs. untargeted sequences.

This app is available in BaseSpace Sequence Hub. Users can select up to 35 individual samples or project folders containing any number of samples for analysis. The app provides results in four different formats: (1) summary report (PDF), (2) annotated mutation table for SARS-CoV-2 and Influenza A/B (TSV), (3) SARS-CoV-2 consensus genome (FASTA), and (4) detailed text-based report (JSON).

Access this app in BaseSpace Sequence Hub

See the Explify Respiratory ID/AMR Analysis User Guide for more info.

Frequently Purchased Together

Specifications

Product Comparison

Respiratory Pathogen ID/AMR Enrichment Panel Kit (Powered by IDbyDNA Explify) Respiratory Virus Oligo Panel
Assay Time < 9 hours library prep time < 9 hours library prep time
Automation Capability Liquid Handling Robots Liquid Handling Robots
Description A streamlined workflow using Respiratory Pathogen ID/AMR Panel (RPIP) with Illumina RNA Prep with Enrichment, sequencing on Illumina desktop systems, and powerful analysis using IDbyDNA’s Explify Platform allows researchers to identify respiratory infections and co-infections, identify antimicrobial resistance, and perform strain typing of critical pathogens (SARS-CoV-2 and Flu A/B viruses) to study viral evolution and transmission. A streamlined workflow for detecting and analyzing SARS-CoV-2 and other common respiratory viruses using RNA Prep for Enrichment combined with Respiratory Virus Oligo Panel for library prep, proven Illumina sequencing, and simplified data analysis using the DRAGEN RNA Pathogen Detection App or IDbyDNA Explify RVOP app on BaseSpace Sequencing Hub.
Hands-on time < 2 hours library prep time < 2 hours library prep time
Multiplexing Up to 384 samples in a single run with unique dual indexes Up to 384 samples in a single run with unique dual indexes
Species Category Bacteria, Fungal, Virus Human, Virus
Species Details Detects respiratory pathogens (180+ bacteria, 50+ fungi, and 40+ viruses, including SARS-CoV-2) and antimicrobial resistance alleles (1200+). Detects common respiratory viruses, including recent flu strains and SARS-CoV-2. Includes human probes as a quality feature, human probes are included in every sample.
System Compatibility MiniSeq , MiSeq , MiSeq, NextSeq 550 MiniSeq , MiSeq , MiSeq, NextSeq 550

Example Workflow

 

Supporting Data and Figures

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